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¹Beyoğlu Göz Eğitim ve Araştırma Hastanesi, İstanbul, Uzm. Dr.
²Beyoğlu Göz Eğitim ve Araştırma Hastanesi, İstanbul, Doç. Dr.
³Beyoğlu Göz Eğitim ve Araştırma Hastanesi, İstanbul, Asist. Dr. Purpose: To evaluate the efficacy and results of photodynamic therapy (PDT) in the treatment of chronic central serous chorioretinopathy (CSC) which persists longer than six months.
Material and Methods: Fifteen eyes of 14 patients with subfoveal fluid which persisted longer than 6 months were included in the study. Visual acuities and contrast sensitivities of the patients were measured before and after the treatment. Infrared fundus photographies, fundus fluorescein and indocyanine green angiographies were performed. Central macular thickness and macular volume values were obtained with optical coherence tomography.
Results: The mean age of the patients was 49±6.3 years. Mean follow-up period was 15.3±13.6 months. Visual acuity (VA) increased more than 2 lines in 12 (80%) eyes after PDT. Visual acuity decreased 1 line in 1 (6.6%) eye; remained unchanged in 1 (6.6%) eye and increased 1 line in 1 (6.6%) eye. The mean contrast sensitivity did not change significantly after PDT. A statistically significant decrease in the mean central macular thickness and total macular volume was observed after the treatment compared to pretreatment (p=0.001). Eleven (73.3%) eyes had complete resolution and 4 (26.7%) eyes had partial resolution of subretinal fluid in OCT. No complication was observed due to PDT.
Conclusion: Photodynamic therapy reduced subretinal fluid and improved visual acuity in patients with chronic CSC of longer than six moths duration. Photodynamic therapy was considered as a safe and effective method in the treatment of chronic CSC. Keywords : Central serous chorioretinopathy, photodynamic therapy, visual acuity