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Celal Bayar Ü.Tıp Fak.Göz Hast.AD, Manisa Purpose: To investigate the relationship between presence of diabetic retinopathy and haematologic parameters.
Method: Sixty two patients with type II diabetes were divided into 3 groups as without retinopathy, non-proliferative diabetic retinopathy and proliferative retinopathy by ocular fundus examination. Afterwards, the following haematologic parameters were examined: haemoglobin, haematocrit, eritrocyte, leucocyte, mean corpuscular volume (MCV), fibrinogen, protrombin time (PT), activated partial tromboplastin time (APTT), protein S and protein C. Results were compared between groups by variance analyses.
Results: Thirty-seven cases were determined as without retinopathy, 10 cases as with non-proliferative retinopathy, 15 cases as with proliferative retinopathy. Eritrocyte counts were significantly higher in cases without retinopathy (p=0.023). Haemotocrit and haemoglobin values showed a tendency to decrease in cases with retinopathy compared to cases without retinopathy, but this was statistically insignificant (p>0.05). Other haematologic parameters were not statistically different between groups (p>0.05).
Conclusions: Results of the study suggested that diabetic retinopathy development was not associated with defects in plasma coagulation system or increases in serum viscosity. The significantly higher eritrocyte count in cases without retinopathy and the tendency of heamoglobin and haemotocrit values to decrease in cases with retinopathy leads one to think that anemia may be a risk factor for retinopathy development. Keywords : Diabetes, retinopathy, haematologic parameters