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¹M.D. Sivas Numune Training and Research Hospital, Eye Clinic, Sivas/TURKEY
²M.D. Kilis State Hospital, Eye Clinic, Kilis/TURKEY
³M.D. Sivas Numune Training and Research Hospital, Radiology Clinic, Sivas/TURKEY
⁴M.D. Professor, Cumhriyet University Faculty of Medicine, Department of Ophthalmology, Sivas/TURKEY Primary Toxoplasma Gondii infection of the mother during pregnancy can cause congenital infection and sequela in the fetus via transplacental passage. In this case report we would like to present a 48 days old infant who was hospitalised with initial diagnosis of central nervous system infection and was consulted to ophtalmology department with suspicion of chorioretinitis and congenital infection. In ophtalmologic examination, the light and object pursuit in both eyes were present and the anterior segment was normal. Fundus examination revealed retinitis focus with scaring edges and active center in both macula with a diameter of 1.5 times the size of the optic disc. At computerised tomography of the brain shallow posterior fossa, diffuse calcification foci in basal ganglia and periventricular regions and dilatation in ventricular system was noticed. Toxoplasma IgG and IgM was positive. Spiramycin 2x175 mg, trimetoprim+sulfometaksazol 2x11 mg was given as antibiotheraphy and 3 days after the antibiotics dexametasone 4x0.45 mg was added. Two weeks later the patient worsened and could not perform the light and object pursuit and died in a few days time. In conclusion we think that even though most of the cases with congenital toxoplasmosis are asymtomatic, routine examination of the pregnant woman including the first trimester are necessary to prevent the catastrophic sequela via early diagnosis and treatment. Keywords : Chorioretinitis, congenital infection, congenital toxoplasmosis, hydrocephalus