2Doç. Dr., Yıldırım Beyazıt Üniversitesi Tıp Fakültesi, Göz Hastalıkları Bölümü, Ankara, Türkiye Purpose: Comparison of intravitreal ranibizumab (IVR) and dexamethasone (IVD) in branch retinal vein occlusion(BRVO)
Materials and Methods: Fifty-five patients with BRVO and macular edema were treated with IVR (Group 1) in 32 patients and IVD (Group 2) in 23 patients.Groups were compared in terms of age, gender, ischemia, duration of post-edema application, number of intravitreal injections. Intraocular pressures (IOP), central macular thickness (CMT) and logarithmic visual acuity (LVA) values were evaluated before injection, after injection 1 month, 3 months, 6 months. SPSS 16.0 program was used for statistical analysis.
Results: Ischemia was present in 8 patients in group 1 and 13 patients in group 2 (p = 0.005) The number of injections was 2.41 ± 1.15 in group 1 and 1.66 ± 0.48 in group 2 (p = 0.007) IOP was signifi cantly higher in group 1 at 6 th month (p = 0.018) and in group 2 at 3 rd month (p = 0.049) There was no statistical difference between LVA 3 and LVA 6 in group 1(p=0.238), İn other values there was a high visual level at statistically signifi cant (p <0.05) increasing up to 6 months. Although there was no statistical difference between LVA 1 and LVA 3 in group 2 (p = 0.097) and between LVA 3 and LVA 6 (p = 0.397), there was an increased visual level until the 6th month. There was statistically signifi cant difference between the other CMT values (p <0.05), although there was no statistical difference between CMT 3 and CMT 6 in Group 1 (p = 0.238) In group 2, there was no signifi cant difference between CMT 1 and CMT 6, and between CMT 3 and CMT 6 (p values 0.985, 0.414) other CMT values were statistically different. (P <0.05)
Conclusion: In intraocular pressure IVR group 6th month, IVD group 3rd month was higher. LVA was running low until 6th month. While CMT decreased in the IVR group until the 6th month, In the IVD group, there was a decrease in the fi rst month, a increase in the third month, and a decrease in the sixth month.
Keywords : Intravıtreal injection,dexametazon ımplant,ranibizumab,branch vein occlusion