2Uz. Dr., Serbest Hekim, Göz Hastalıkları, İstanbul, Türkiye
3Uz. Dr., Okmeydanı Eğitim ve Araştırma Hastanesi, Göz Hastalıkları, İstanbul, Türkiye
4Prof. Dr., Serbest Hekim, Göz Hastalıkları, İstanbul, Türkiye Purpose: To assess the changes in inner retinal layers and choroidal thickness in diabetic patients using spectral domain optical coherence tomography (SD-OCT).
Materials and Methods: We examined 60 eyes of 43 diabetic patients with diabetic retinopathy (as Group 1), 89 eyes of 47 diabetic patients without diabetic retinopathy (as Group 2) and 88 eyes of 46 age and sex matched individuals without diabetes (as control group). The thickness of retinal nevre fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL) and choroid measured by SD-OCT.
Results: In Group 1 patients, thickness of RNFL were found to be signifi cantly thinner than other groups in central subfi eld (p=0.009, p=0.012). In Group 1, thickness of GCL were found to be signifi cantly thinner than Group 2 in all inner fields (p=0.005, p=0.011, p=0.002, p=0.015). In Group 1, thickness of GCL were found to be signifi cantly thinner than control group in central subfi eld, inner nasal, temporal and superior fields (p=0.015, p=0.001, p=0.010, p=0.010). In Group 1, thickness of IPL were found to be signifi cantly thinner than other groups in inner nasal, temporal and superior fields (p=0.006, p=0.001, p=0.001 and p=0.009, p=0.001, p=0.003). No signifi cant difference was found between groups in terms of choroidal thickness (p>0.05).
Conclusions: In diabetic patients, it was observed that the thickness of the ganglion cell and internal plexiform layer decreased as a result of microvascular and neurodegenerative changes. Although there were no statistically signifi cant differences between the groups, the choroidal thickness tend to be thicker in diabetic patients.
Keywords : Diabetes mellitus, optical coherence tomography, retinal thickness, choroidal thickness