2Asist. Dr., Bakırköy Dr. Sadikonuk Eğitim ve Araştırma Hastanesi, Göz Kliniği, İstanbul, Türkiye Purpose: The aim of this study was to investigate the contribution of fl uorescein angiography fi ndings to the diagnosis, classifi cation, follow-up and treatment of the disease in patients with the diagnosis of familial exudative vitreoretinopathy (FEVR) that were referred to our clinic.
Materials and Methods: Twenty-eight eyes of 14 patients diagnosed with FEVR based on clinical fi ndings were included in the study. Wideangle fluorescein angiography (FA) was performed with the RetCam III (Imaging System Clarity Medical Systems, Pleasanton, CA, USA) in all patients under sedation and staging of the disease was performed based on angiographic findings.
Results: The mean gestational age of the patients in the study was 38.57 ± 1.45 (36-40) weeks, the mean birth weight was 2745 ± 731.09 (800- 4000) grams and the mean age was 47.75 ± 51.09 (3- 168) months. Eleven eyes (39.28%) had stage 1a, 2 eyes (7.14%) had stage 1b, 1 eye (3.75%) had stage 2a, 11 eyes (39.28%) had stage 2b, 1 eye (3.75%) had stage 3 FEVR and stage 5 FEVR was detected in 2 eyes (7.14%) of 2 patients. Laser photocoagulation was performed to all eyes with leakage on fluorescein angiography. Two eyes of 2 patients had vitreoretinal surgery for stage 5 FEVR. Laser photocoagulation was applied to the fellow eyes of these patients with the diagnoses of stage3 and 1a disease.
Conclusion: Wide-angle fl uorescein angiography is important in the diagnosis, treatment decision and follow-up of FEVR. With sedation for children under 5 years of age, the detection of the risk of progression before development of vision-threatening complications of FEVR is possible.
Keywords : Familial exudative vitreoretinopathy, Wide-angle fl uorescein angiography