Retina-Vitreous
2020 , Vol 29 , Num 3
Diagnostic Testing in Uveitis
1MD., Koç University School of Medicine, Department of Ophthalmology, Istanbul, Turkey2MD., Koç University Research Center for Translational Medicine, Istanbul, Turkey DOI : 10.37845/ret.vit.2020.29.34 Uveitis is the inflammation of uveal tissue which includes a multitude of ocular and systemic disorders. Diagnostic tests are of crucial importance to defi ne both infectious and non-infectious etiologies in uveitis. In this measure, an armamentarium of laboratory tests including blood and fluid serologies, ocular fluid/tissue sampling and imaging modalities are available for clinical diagnosis of uveitis. However, the predictive values of these tests are highly dependent to the patients? clinical findings and epidemiological factors. Therefore, clinical data acquired from patient history and examination should provide a reference for choosing diagnostic tests in order to prevent misinterpreting test results that would lead to wrong diagnosis and treatment decisions. In this review, we will discuss the diagnostic tests that are frequently used in uveitis practice and their power to predict true diagnosis on a statistical perspective. Keywords : Uveitis; diagnostic tests; serology, Bayesian statistics; likelihood ratio, Positive predictive value