Methods: A prospective non-randomized case-control study on 49 patients with various CSCRs underwent Spectral-Domain Optical Coherence Tomography (SD-OCT) at baseline and six months and Fundus fluorescein angiography (FFA) to all non-resolving recurrent cases. Profession profile was assessed by categorized into blue-collar, white-collar jobholders, self-employed, and others. The patient?s current psychological state was assessed by a general health questionnaire (GHQ12). Two sets of similar questionnaires were given to cases, and controls (age/ gender-matched with problems other than CSCR) and non-professionals were given a single questionnaire to assess their psychological state in two different environments.

Results: High prevalence of CSCR was observed in blue collars (63%) followed by white-collar (14%) jobholders, self-employed (4%), and others (19%). Recent psychological stress scores were significantly higher in cases compared to controls (t=5.147, p<0.001). Dependency of type of presentation on the recent psychological state was not significant (p= 0.25). Dependency of central foveal thickness (CFT) and visual acuity (VA) on the psychological state is statistically significant (p<0.01).

Conclusions: This study was the first study to evaluate the professional status and psychological stress of CSCR patients in the Indian population. Higher psychological stress scores observed in CSCR, especially blue-collar jobholders. These higher psychological stress score patients showed more CFT and worse VA at baseline. The structural and functional outcomes of all CSCR were similar at 6 months follow-up. Keywords : Central Serous Chorioretinopathy, Optical Coherence Tomography, General Health Questionnaire, Central Foveal Thickness, Visual Acuity