2Prof., Mugla Sitki Kocman University, Ophthalmology Department, Mugla, Turkey
3Assoc. Prof., Mugla Sitki Kocman University, Ophthalmology Department, Mugla, Turkey
4MD, Mugla Sitki Kocman University, Ophthalmology Department, Mugla, Turkey
5Assoc. Prof., Mugla Sitki Kocman University, Ophthalmology Department, Mugla, Turkey DOI : 10.37845/ret.vit.2023.32.30 Purpose: To compare the microvasculature and fundus morphometric features between the high myopic eyes with and without the beta zone peripapillary atrophy (?-PPA).
Methods: 38 eyes with high myopia (mean spherical equivalent (MSE) ?- 6.00D) and 30 age-matched emmetropic eyes (- 1.00 ? MSE<+0.75D) were included in this prospective study. Two groups were created according to presence of ?-PPA. Group 1 consisted of 26 eyes with normal OD, and group 2 consisted of 12 eyes with ?-PPA. The vertical distance between the temporal superior and temporal inferior arterial arcade (VDA), the distance fovea to disc (DFD), and optical coherence tomography angiography (OCTA) were compared between the groups.
Results: The mean VDA and DFD were higher in group 2 than group1 and control group. The mean foveal avascular zone was larger and peripapillary VD was lower in all myopic eyes regardless of the presence of ?-PPA in group 1 and 2 than the controls. (For FAZ p<0.001, p=0.002; for peripapillary VD p=0.049, p=0.004) The parafoveal VD in deep capillary plexus and VD of optic nerve head (ONH) were lower in group 2 than group 1. (For parafoveal VD p=0.015; for total disc VD p=0.008; for peripapillary VD p=0.017) There was a mild negative correlation between DFD and parafoveal VD and peripapillary VD in high myopic eyes. (r=-0.344, p=0.004; r=-0.365, p=0.002)
Conclusions: VD of ONH and parafovea was lower in high myopia with ?-PPA. Decreased parafoveal and peripapillary VD was correlated with the elongation of the DFD.
Keywords : High myopia, Vessel density, Distance fovea to disc, Optical coherence tomography angiography, Beta zone peripapillary atrophy