Materials and Methods: The records of patients diagnosed with CRAO between January 2017 and April 2023 at Ondokuz Mayis University Hospital were retrospectively reviewed. Treatments and detailed ophthalmological examination findings at the baseline and post-treatment follow-up of the patients were recorded. After ocular massage and acute antiglaucomatous treatment; the patients were divided into 3 groups, as group 1 received HBO therapy after anterior chamber paracentesis (ACP), group 2 received only HBO therapy, group 3 received only ACP. Data were analysed with the IBM SPSS Statistics 22 program using non-parametric tests.

Results: Thirty-four patients with a median age of 72 (28-92), 12 (35.3%) women and 22 (64.7%) men, were included in the study. There were 10, 14, and 10 patients in groups 1, 2 and 3, respectively. The groups were similar in terms of age, gender, systemic diseases and time of admission (p >0.05). In groups 1, 2 and 3: baseline median visual acuity (VA) was 2.3 (2.3-3.0), 2.3 (1.3-3.0), and 2.3 (1.3- 3.0) logMAR (p =0.573); the median VA at last visit was 1.9 (0.3-3.0), 1.9 (0.3-3.0), and 2.5 (1.3-3.0) logMAR (p =0.624), respectively. Only in group 1, the final VA increased significantly from baseline (p =0.035), while no significant change in VA was observed in the other groups (p =0.138 and p =0.786 for groups 2 and 3, respectively). Final VA was moderately positively correlated with baseline VA (r =0.425, p =0.012) and moderately negatively correlated with time of admission (r =-0.381, p =0.026).

Conclusion: HBO therapy combined with ACP applied in the early period in the treatment of CRAO positively affects the visual prognosis. Keywords : Hyperbaric oxygen, anterior chamber paracentesis, central retinal artery occlusion, CRAO