Retina-Vitreous
2007 , Vol 15 , Num 2
Use of Fundus Autofluorescence in Hereditary Retinal Diseases
1GATA Haydarpaşa Eğit. Hast., Göz Hast. Klin., İstanbul, Doç. Dr.2GATA Haydarpaşa Eğit. Hast., Göz Hast. Klin., İstanbul, Yard. Doç. Dr.
3GATA Haydarpaşa Eğit. Hast., Göz Hast. Klin., İstanbul, Prof. Dr. Fluorescence is the property of some molecules to emit light energy of a longer wavelenght when stimulated by a light of a certain wavelength. Autofluorescence, on the other hand, is emission of fluorescent light from ocular structures in the absence of fluorescein sodium. Fundus autofluorescence (FAF) has been recently introduced as a technique of fundus imaging and is considered to originate from lipofuscin in retinal pigment epithelium (RPE). Hence, this technique can noninvasively evaluate the RPE. FAF can be recorded by specially modified fundus cameras or scanning laser ophthalmoscopes, and it has been used successfully in different retinal disorders. This technique reveals typical findings in patients with hereditary retinal diseases. FAF is an imaging technique that can effectively be used in hereditary retinal disorders. It may reveal RPE lipofuscin changes not ophthalmoscopically visible, and it may provide typical images not seen by fluorescein angiography or ophthalmoscopy. Keywords : Autofluorescence, fundus autofluorescence, hereditary retinal disorders