Retina-Vitreous
2007 , Vol 15 , Num 3
Fibrinous Reaction After Vitreoretinal Surgery: Risk Faktors and Clinical Presentation
1Gazi Ü.T.F. Göz Hastalıkları A.D., Ankara, Asist. Dr.2Gazi Ü.T.F. Göz Hastalıkları A.D., Ankara, Doç. Dr.
3Fatih Ü.T.F. Göz Hastalıkları A.D., Ankara, Uzm. Dr.
4Gazi Ü.T.F. Göz Hastalıkları A.D., Ankara, Prof. Dr. Purpose: Preoperative, intraoperative and postoperative factors affecting degree and the formation of pupillary fibrinous membrane after vitreoretinal surgery and its clinical presentation.
Materials and Methods: 68 eyes of 68 patients who developed fibrinous reaction in the anterior chamber after vitreoretinal surgery at Gazi hospital ophthalmology department has analyzed retrospectively. Detailed review of their surgical technique, systemic diseases, and preoperative, intraoperative, and postoperative data were included. Daily postoperative follow up, biomicroscopic anterior segment examination, ocular tension measurement with Goldman applanation tonometer and fundus examination were done in the patients with postoperative fibrinous membrane. Aggressive topical steroid treatment was given until the fibrinous membranes disappeared.
Result: Postoperatively, 32 patients developed thin pupillary membrane while 36 patients developed thick pupillary membrane. 45 patients (66.2%) were males and 23 patients (33.8%) were females. Mean age was 39.56±21.16 year. There was no statistical difference between thin and thick pupillary membrane regarding age, sex and systemic diseases. But the rate of diabetes mellitus in the thin and thick pupillary membrane was 15.6% and 27.8% respectively. Mean appearance time of pupillary membrane in the thin and thick groups was 1.52±0.77 day and 1.62±0.77 day respectively (p=0.48). While mean disappearance time was 24.1 days and 30.9 days respectively (p=0.03). 26 eyes (38.2%) of patients with pupillary membrane had had previous vitreoretinal surgery and 30 patients (44.1%) were having combined cataract and vitreoretinal surgery at the time of appearance.
Conclusions: the risk factors possibly included in the formation of pupillary membrane were diabetes mellitus, previous vitreoretinal surgery, lens extraction and retinal manipulation. In the majority of the patients who was treated with heavy topical steroids theirmembrane disappeared without serious complications. Keywords : Pupillary membrane, vitreoretinal surgery, fibrinous reaction