Retina-Vitreous
2008 , Vol 16 , Num 2
Use of Fundus Autofluorescence in Macular Hole
1GATA Haydarpaşa Eğitim Hastanesi, Göz Hastalıkları Kliniği, İstanbul, Yard. Doç. Dr.2Yeditepe Universitesi Tıp Fakültesi, Göz Hastalıkları Kliniği, İstanbul, Doç. Dr.
3GATA Haydarpaşa Eğitim Hastanesi, Göz Hastalıkları Kliniği, İstanbul, Doç. Dr.
4GATA Haydarpaşa Eğitim Hastanesi, Göz Hastalıkları Kliniği, İstanbul, Prof. Dr. Purpose: Fundus autofluorescence (FAF) has been recently introduced as a new technique for fundus imaging and is considered to originate from lipofuscin molecules in retinal pigment epithelium. The purpose of the current study was to present the FAF images of patients with macular hole.
Materials and Methods: FAF images of 10 patients with macular hole were recorded. A scanning laser ophthalmoscope (HRA2, Heidelberg Retina Angiograph 2) was used for FAF imaging. To increase the quality and contrast of the fluorescence signal, 32 single images were averaged using HRA2 software.
Results: FAF imaging revealed an area of hyperAF corresponding to the macular hole with a surrounding area of hypoAF in all cases.
Conclusion: FAF is a non-invasive imaging technique for assessing patients with macular hole. It can be of value in the differential diagnosis of macular hole and in cases in which fluorescein angiography may be undesirable.
Keywords : Autofluorescence, fundus autofluorescence, macular hole, lipofuscin, melanin.