Retina-Vitreous
2008 , Vol 16 , Num 4
Near-Infrared Fundus Autofluorescence in Hereditary Retina Diseases
1Yeditepe Üniversitesi Tıp Fakültesi Göz Hastalıkları A.D., İstanbul, Doç. Dr.2GATA Haydarpaşa Eğitim Hastanesi, Göz Hastalıkları Kliniği, İstanbul, Yard. Doç. Dr.
3GATA Haydarpaşa Eğitim Hastanesi, Göz Hastalıkları Kliniği, İstanbul, Prof. Dr. Fluorescence is the property of certain molecules to emit light energy of a longer wavelenght when stimulated by a light of a shorter wavelength. Autofluorescence is emission of fluorescent light from ocular structures in the absence of any fluorescent dye. Due to the presence of autofluorescent molecules in the ocular fundus, it is possible to obtain fundus images by using special filters. This method is named as fundus autofluorescence (FAF) imaging. FAF term is generally used as 488 nm blue lightinduced imaging modality, and is reported to originate from lipofuscin in retinal pigment epithelium (RPE). Near infrared autofluorescence, on the other hand, is obtained at 787 nm excitation
wavelength using a barrier filter for detection of emitted light above 810 nm. Melanin in RPE and choroid is the main fluorophore for near infrared autofluorescence. In this report, near infrared autofluorescence findings of some hereditary retinal disorders are presented. Keywords : Autofluorescence, fundus autofluorescence, near infrared autofluorescence, hereditary retinal disorders