Retina-Vitreous
2008 , Vol 16 , Num 4
Treatment of Choroidal Neovascular Membrane Secondary to Radiation Retinopathy
1S.B. Ankara Atatürk Eğit. ve Araş. Hast. 1.Göz Kliniği, Ankara, Uzm. Dr.2S.B. Ankara Atatürk Eğit. ve Araş. Hast. 1.Göz Kliniği, Ankara, Asist. Dr.
3S.B. Ankara Atatürk Eğit. ve Araş. Hast. 1.Göz Kliniği, Şef Yardımcısı, Ankara, Doç.Dr.
4S.B. Ankara Atatürk Eğit. ve Araş. Hast. 1.Göz Kliniği, Klinik Şefi, Ankara, Prof. Dr. A 42-year-old woman applied to our clinic with gradually decreasing visual acuity in her right eye. She had undertaken radiotherapy for nasopharynx cancer 3 years ago. Her visual acuity was counting fingers in the right eye, and 10/10 in the left eye. In her fundus examination; hemorrhage, exudation, and serous elevation was detected in the right eye, and microaneurysms were detected in the left eye. FFA revealed choroidal neovascular membrane with indefinite margins in the right eye, and microaneurysms in the left eye. OCT showed hyperreflectivity pertaining to CNVM and cystoid macular edema on the right eye, while the left eye was normal. ICG revealed occult membrane in the right eye, while the left eye was normal. Single session of photodynamic treatment was applied to the patient’s right eye, followed by intravitreal bevacizumab injection 24 hours later. In the 1 month control examination, visual acuity had improved to 1/10, FFA showed occluded CNVM, and OCT showed normal macular thickness in right eye. CNVM may rarely develop in radiation retinopathy cases, but it can be successfully treated with photodynamic treatment combined with intravitreal bevacizumab. Keywords : Radiation retinopathy, choroidal neovascular membrane, photodynamic therapy intravitreal bevacizumab