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Selcuk University, Faculty of Medicine, Department of Ophthalmology, Konya/TURKEY Diabetic retinopathy encompasses a group of predominantly microvascular anomalies. Fundus fluorescein angiography (FFA) which is superior to colour fundus photography in detecting these lesions, is especially useful to decide on the type and treatment for diabetic macular edema. Though FFA and optical coherence tomography findings are correlated usually, FFA may reveal the morphologic changes earlier than OCT. The spectrum of morphologic changes in FFA of a patients with diabetic retinopathy may be categorized as hyperfluorescent lesions like microaneurysms, intraretinal microvaascular abnormalities and neovascularizations; hypofluorescent lesions like exudates, hemorrhages, cotton-wool spots, non-perfusion areas and vascular abnormalities. The advent of wide-field angiogram provided further the opportunity to visualize the peripheric abnormalities like peripheral vascular leakage and peripheral non-perfusion areas which show strong correlation with focal macular edema and foveal avascular zone enlargement. Another imaging method- indocyanine green angiography may detect diabetic choroidopathy earlier than FFA. As these informations indicate angiography provides non-replacable informations of utmost importance for the follow-up and treatment of a diabetic patient. Keywords : Fundus fluorescein angiography, diabetic retinopathy, diabetic maculopathy, indocyanine green angiography, wide field angiography