2Uz. Dr., Erciyes Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Kayseri, Türkiye
3Asist. Dr., Erciyes Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Kayseri, Türkiye
4Yrd. Doç. Dr., Erciyes Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Kayseri, Türkiye Purpose: Evaluation of the relationship between macular optical coherence tomography (OCT) parameters with visual functions in patients with retinitis pigmentosa (RP).
Materials and Methods: Demographic data and parameters of spectral domain-OCT of patients with RP whom applied to our clinic were evaluated retrospectively. One hundred and fi fty-three eyes of 79 patients were included into the study. Mean visual acuity of the patients were converted to logMAR values. Vitreoretinal surface abnormalities, presence of cystoid macular edema (CME) and integrity of the outer retinal layers were evaluated, and central macular thickness (CMT) was calculated with OCT.
Results: Mean visual acuity was 1.2 ± 0.9 logMAR. Median CMT was 154 ?m (41-873) in RP group. This value was 267 (173-873) ?m in cases with CME, and 140 ?m (41-296) when cases with CME were withdrawn. There was a negative correlation between the patients? ages and visual acuities with their CMT. Twelve of the eyes (8%) had epiretinal membrane while 9 eyes (6%) had macular hole. All patients had disintegrity of outer retinal layers of varying degrees.
Conclusion: With the aging and progression of the disease, visual acuity tend to decrease, central macula thins and disintegrity in the outer retinal layers increases. Patients have a signifi cant correlation between OCT changes and visual functions. Optical coherence tomography is very helpful in determining retinal structure, morphological abnormalities and assessing the prognosis in patients with RP.
Keywords : Cystoid macular edema, macula, optical coherence tomography, retinitis pigmentosa, central macular thickness