Retina-Vitreous
2012 , Vol 20 , Num 1
Retinal Vein Occlusion in Young Patients: Combined MTHFR and PAI-1 Mutations
1M.D. Asistant Professor, Abant İzzet Baysal University, Department of Ophthalmology, Bolu/TURKEY2M.D. Professor, Abant İzzet Baysal University, Department of Ophthalmology, Bolu/TURKEY
3M.D., Asistant Professor, Abant İzzet Baysal University, Department of Medical Genethics, Bolu/TURKEY
4M.D. Professor, Yıldırım Bayazıt Training and Research Hospital Hematologies Clinic, Ankara/TURKEY In this case presentation, we reported 3 young patients with retinal vein occlusion. None of the patients showed any risc factors at the end of detailed systemic examinations. Methylenetetrahydrofolate reductase C677T and A1298C with plasminogen activator inhibitor-1 heterozygote gene mutations were detected in all patients on genetic analysis. The presence of thrombophilic risk factors should be considered in young patients with central retinal vein occlusion. Keywords : Retinal vein occlusion, young adults, thrombophilic risk factors