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M.D. Professor, Gazi University Faculty of Medicine, Department of Ophthalmology, Ankara/TURKEY This paper discusses the technique, efficacy and complications of the focal-grid laser for the treatment of diabetic macular edema. The place of laser treatment in the era of intravitreal pharmacotherapy, the new developments in laser technology like subtreshold micropulse laser and focal navigated laser technology were also discussed. Keywords : Laser treatment, diabetic macular edema, new developments, micropulse laser